GGP Equine

SKU No.  457  |  Catalog No. 

GGP Equine is a robust and multipurpose tool that serves as a foundation for many research and commercial applications.

  • Genome-wide association studies
  • Identification of genes and polymorphisms that contribute to traits of interest
  • Development of genomic predictions and enhanced breeding values
  • Foundation for validation, translation, delivery of health, and trait markers to users such as horse owners, breeders, and veterinarians
$35.00 each
In stock
Out of stock
Expect availability in 2-4 weeks
Minimum quantity required: 1
This item must be ordered in multiples of one case. Quantity per case: 1

Originally based on Illumina’s Equine SNP50 platform, this beadchip was created with data generated by the Equine Genome Mapping Workshop and Broad Institute’s Equine Genome Sequencing Project using SNPs from Arabian, Andalusian, Akhal-Teke, Icelandic, Standardbred, Thoroughbred, and Quarter Horse breeds. Our GGP Equine has undergone multiple iterations to improve coverage and minor allele frequency across many major horse breeds. Developed using the Multiple Objective Local Optimization (MOLO) algorithm1, GGP Equine includes over 70,000 evenly distributed single nucleotide polymorphisms (SNPs) with an average minor allele frequency of 0.26.

In addition to SNP content available for research and discovery, GGP Equine also includes specific published markers associated with relevant health conditions, physical traits, Y chromosome markers, and over 1000 mitochondrial markers useful for research and breeding organizations.

Specifications
BrandGeneSeek® Genomic Profiler™
SpeciesEquine
Assay Sample SizeSubmit samples in batches of 24
Submission Information

DNA requirement is 300–500 ng at 20 ng/ul concentration.

DNA samples can be shipped in screw-cap tubes or PCR plates. It’s best to send DNA dried down at low temp to avoid evaporation or leakage during transport. DNA in suspension should be shipped on dry ice.

Genetic ConditionsCerebellar abiotrophy, Epidermolysis bullosa, junctionalis, Hyperkalemic periodic paralysis II (HYPP), Dwarfism with joint laxity, HERDA — hereditary equine regional dermal asthenia, Hydrocephalus, Incontinentia pigmenti, Malignant hyperthermia, Myotonia, Naked foal syndrome, SCID — severe combined immuneodeficiency, Glanzmann thrombasthenia, Multiple ocular defects, Lavender foal syndrome, Warmblood fragile foal syndrome, Polysaccharide storage myopathy / exertional rhabdomyolysis, Congenital stationary night blindness, Ocular squamous cell carcinoma, Dwarfism, ACAN-related , Androgen insensitivity syndrome (AIS), Gilbert-meulengracht syndrome, Congenital hepatic fibrosis 1, Foal immunodeficiency syndrome, Lordosis (swayback) , Curiosity and vigilance, Equine recurrent uveitis, Extension (red/black factor), Modifying mutation to extension, Recessive black (agouti), Cream dilution, Pearl, Silver, Champagne, Frame overo (lethal white overo), Tobiano, Leopard complex spotting, Curly hair variant 1, Curly hair variant 2, Dominant white (W1-W23), Macchiato, Brindle / incongenitia pigmenti, Brindle (BR1), Sabino, Splashed white 1, Splashed white 2, Splashed white 3, Splashed white 4, Pattern 1 (PATN1), Body size, Pony size
Turnaround TimeApproximately 3-4 weeks
Research References1. Wu XL, Xu J, Feng G, Wiggans GR, Taylor JF, et al. (2016) Optimal Design of Low-Density SNP Arrays for Genomic Prediction: Algorithm and Applications. PLOS ONE 11(9): e0161719. https://doi.org/10.1371/journal.pone.0161719

Additional Information

Data can be made available on either EquCab 2.0 or 3.0 mapping positions.

DNA extraction services available — contact us for details.

Patent restrictions may apply to genetic condition markers depending on region and application — contact us for more details.

Training

Our customers’ success is our shared success. Our customer service teams are ready to assist you and your team on our solutions, so you can rest easy knowing sampling procedures are performed properly and yield accurate results.